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Yesterday Navigraph released their new charts product also including a new pricing scheme. ![]() #SKYMAXX PRO SCREENSHOT COMPARISON HOW TO#I will probably do a teardown of the internal components and document that, try to research the past of the unit based on the accompanying papers and document how to connect the displays, if I can figure the interface out (otherwise I will just replace them). I will put more information on it on this blog when it arrives. The picture (taken by the seller) shows my CIVA. The only solution to all of this – of course – is to buy a real Delco Carousel IV-A Control Display Unit and wire that up! Unfortunately a lot of people seem to want their external full-blown FMC CDUs, but nobody cares about an external INS control unit. So it would be best to get a pre-assembled unit of some sort. Usually projects like this end in me buying a lots of stuff and never wiring it up to actually get it running. All of this, of course, while still matching the original unit as closely as possible. #SKYMAXX PRO SCREENSHOT COMPARISON FULL#On the device end though this would envolve wiring up a few seven-segments displays, a full numpad-style keyboard as well as the waypoint selector wheel. #SKYMAXX PRO SCREENSHOT COMPARISON PC#Luckily Philipp added proper datarefs for interfacing with the simulated device, so on the PC side this should not be too much effort to implement (see section 12 of the manual). This together with the fact that it can be very annoying to enter the information using the mouse pointer finally gave me the idea to build my own CIVA control unit input device to connect to my computer. Unfortunately it was only added to the right hand side of the cockpit, so it is not easily visible from the captain's side when the throttles are advanced forward (see also this thread on the FlyJSim forums). I really like the CIVA for flights without good VOR coverage, so I greatly appreciate the addition as a 3-D object. In the same process Jack also added a 3-D CIVA INS (requires a separate license). I will post anything interesting I can come up with.Īlso I will post some pictures of the internals of the device.įlyJSim recently updated the amazing 732 TwinJet to a newer version which much improved sound, a great new pushback feature and what not. Although I unfortunately did not have any luck in this regard so far. It was last maintained in July 2004 by Northrop Grumman, one year prior to removal from the plane.Īs next steps I will try to dig up some more information, ideally even some wiring diagrams. This story seems absolutely plausible since the unit still wears a Lufthansa inventory sticker on its back (see figure 3). It is nice that the unit made it back to Germany after 10 years in storage in the US, having spent at least 20 years flying exclusively for a German airline. On I found a picture of the unit still mounted in the cockpit (taken early 2003). In 2005 it was sold to Evergreen Internationl Airlines (around the same date the CIVA was removed) and continued to fly in their service until June 2012. #SKYMAXX PRO SCREENSHOT COMPARISON REGISTRATION#This Boeing 747-200 appears to have first flown for Lufthansa in June 1985 (according to planespotters) under the registration D-ABZA and was later, in 1993, modified to a Cargo plane for Lufthansa Cargo. Nicely this tag also reports the aircraft registration number of the plane it was removed from, N488EV, An Evergreen International Airlines aircraft. I assume to replace it with a more modern FMC. Judging from the accompanying Removed Parts Tag (see figure 2) the unit was removed for modification. The thumb-wheel and the mode and test selector all provide the same clicks, you are always sure, what state is currently selected. The switches provide are very springy and provide a satisfying clicking sound when pressed. It came in a much better shape than I expected it to. Today my Delco Carousel IV-A Display Unit arrived from the US. ![]() ![]() ![]() For the first time, we report pharmacokinetics of E2 in guinea pigs after two different doses administered via subcutaneous route.Yang Chen †, Kaijing Zhao †, Fei Liu, Qiushi Xie, Zeyu Zhong, Mingxing Miao, Xiaodong Liu * and Li Liu * The high precision and accuracy with minimal sample volume, no derivatization and short assay run time of 3 mins presents a highly amenable assay for low-level quantitation of E2 in a high-throughput capability. These data suggest that the lower dose of 10 µg/kg E2 administered subcutaneously can achieve physiologically relevant concentration as observed in women lasting up to 12 h in guinea pigs.Ĭonclusion:We developed and validated a novel and sensitive LC-MS/MS assay using OVX guinea pig plasma to successfully obtain the PK profile of E2 in guinea pigs. Similarly, the half-life (t1/2) was 2x higher and plasma clearance was 2x lower after 40 µg/kg dose compared to the 10 µg/kg dose. Like the Cmax, the area under the curve (AUC0-ꚙ) was also 8x higher after 40 µg/kg dose compared to the 10 µg/kg dose suggesting a more than dose proportional increase in plasma concentration after the higher dose. E2 reached an average Cmax of ~540 pg/mL after 10 µg/kg dose whereas the average Cmax was ~4000 pg/mL (8x higher) after 40 µg/kg dose. In PK profiling study, E2 showed rapid absorption following subcutaneous dosing with high Cmax and AUC and elimination half-life of ~3 h. ![]() Dilution integrity assay passed at 10x level with no injection carryover. Stability studies met the acceptance criteria for bench-top, auto sampler, long term storage and freeze-thaw experiments. Absolute mean recovery was ~90% with negligible matrix effect. Intra- and inter-batch precision were <15% and accuracy (☘5-115%) for 6 replicates at 5 different QC concentrations on 3 consecutive days. The method was highly specific with no interference in blank matrix. The assay was linear from 3.90-1000.00 pg/mL with no chemical derivatization. Results:The developed method was validated and found to be robust and sensitive. The plasma concentration data were used to calculate PK parameters of E2 in both the treatment groups by non-compartmental analysis using Phoenix WinNonlin v.6.4. The method was applied to determine the pharmacokinetic (PK) profile of E2 in OVX guinea pigs (weighing 500-700 g) treated with 10 or 40 µg/kg E2, injected subcutaneously and blood samples (~600 µL) collected at 0, 0.25, 0.5, 1, 2, 4, 8, 12 and 24 h after dosing. Method was validated as per 2013 FDA Guidance for Bioanalytical Method Validation. Mass spec (AB Sciex 6500 Q-Trap) was operated in negative ion ESI mode with MRM transitions at m/z 271.0/143.0, 145.0, 183.0 for E2 and 275.0/147.0 for E2-d4, respectively. E2/E2-d4 were resolved on a Kinetex C18 Phenyl-Hexyl column with 0.05% Ammonium hydroxide in water (mobile phase A) and 0.05% ammonium hydroxide in methanol (mobile phase B) in 3.0 min. Liquid chromatography was performed on Agilent 1290 Ultra-High Performance Liquid Chromatograph. Extraction of E2 from 100 µL of OVX plasma was achieved by liquid-liquid extraction using 90:10 tert-butyl methyl ether: hexane solvent mixture. ![]() A working stock solution at 100.00 ng/mL was prepared in 60% methanol. Methods:E2 and E2-d4 (deuterated E2 used as an internal standard) were dissolved in methanol at 1.00 mg/mL. Plasma (with no measurable endogenous hormone levels) from ovariectomized (OVX) guinea pigs was used for preparation of calibrators and quality control specimens. Here, we describe a robust liquid-chromatography tandem mass spectrometry (LC-MS/MS) assay that was developed and validated in-house. To better understand the underlying effects of E2 on drug-induced arrhythmia a prerequisite is to be able to measure the circulating levels in vivo accurately. Because the duration of QT interval is a risk factor for drug-induced arrhythmia, an understanding of how female sex hormones including E2 affect the QT interval is important to understand drug-induced arrhythmia susceptibility in women. In females, QT interval is longer during the follicular phase when the circulating level of estradiol (E2) is high than during the luteal phase when the progesterone-to-estradiol ratio is increased. Purpose:Evidence from clinical and basic science studies suggest that sex differences in susceptibility to some arrhythmias arise directly from fundamental differences in cardiac tissue. ![]() ![]() ![]() At internet solution for proteus 7 is given but when i installed proteus 8 it does . aim in analyzing the success of the design created. I dont have library folder, when i install proteus 8. After that, Apply patch “Update Proteus 8.4 SP0 Demo to PRO . 10 minHow To Install and Download Proteus 8 Professional free and works 100 % in windows (. 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![]() ![]() Some Spanish language translators tend to confuse phrasal verbs and single-word verbs whose meanings are related. The most common errors made by Spanish translators when translating phrasal verbs are semantic errors, which reflect an incomplete understanding of the meaning of phrasal verbs. These verb combinations are a clear example of “Nil Equivalence”, given that they only exist in English. To bring children clearly does not have the same meaning as to bring up children and therefore the verb “bring” needs the adverb “up” in order to convey the meaning “raise children.” According to this example, bring up is a phrasal verb.ĭifficulties arise when English-to-Spanish translators at your translation company need to translate phrasal verbs. It is not easy to bring children nowadays.It is not easy to bring up children nowadays.A characteristic of the phrasal verb is that the individual verb rarely carries the same meaning when the adverb or preposition has been deleted or replaced by another one. In most cases, the meaning of the combined words cannot be determined from the meaning of the verb or the adverb in isolation. The phrasal verb is not considered as two parts but as one lexical unit. Thus the phrase “let’s get together in the social hall after Church” sounds more inviting amongst friends than “let us congregate in the social hall after Church.” How the meaning of a phrasal verb is determined Phrasal verbs are commonly used in informal English speech, to avoid sounding formal or pretentious. Single Verb: Determine the meaning of the error message.Phrasal Verb: Find out the meaning of the error message.For instance, the phrasal verb “find out” can be replaced with “discover” or “determine,” as seen below: The idiomatic meaning allows a phrasal verb to be replaced with a single word verb. Phrasal verbs are particularly common in the English language and a phrasal verb often has a meaning which is quite different from the original verb. Phrasal verbs are sometimes also referred to as ‘compound verb’, ‘verb-adverb combination’, or ‘verb-particle construction (VPC.)’ Any of these combinations are not only part of the syntax of the sentence, but are considered a complete semantic unit as well. Phrasal verb definedĪ phrasal verb is a combination of a verb and a preposition, a verb and an adverb, or a verb with both an adverb and a preposition. ![]() ![]() This blog focuses on just one of the many ways that source English sentence structure can affect the quality of a translation project. Unfortunately, phrasal verbs tend to have a negative impact on language translation, as the meaning of two or three words must be translated to a single verb which may have a very different tone or nuance than the combined words. In fact, many of us who frequently use phrasal verbs are unaware of just exactly what they are! You can find these in GROUP 5.Phrasal verbs are so common in informal English speech that they are used almost unconsciously. There are some other directions that we use less often, including after, through, over, across, around, past, together and apart. Sometimes we use the directional meaning in a metaphorical way. ![]() These directional meanings are in GROUP 1.Įach particle also has some special meanings. We sit by the toy box and put the blocks IN and take them OUT. We sit ON the stool and get OFF the stool. We take a car and pick it UP and put it DOWN. The most frequently used are up/ down, in/ out, on/ off and back/ away. To understand them, you have to understand the little words – we call them particles. Don’t try to learn “Phrasal verbs with take” or “Phrasal verbs with get” or “Phrasal verbs with go”. However, often English course books present them in a completely random way which makes them very difficult to learn. #List of phrasal verbs with meanings in spanish how toHow Phrasal Verbs Work and How to Learn Them ![]() ![]() ![]() You can set that as the intent of the match. How do you do that? The fastest way is to run them in good feuds or have matches that are meant to put them over. You said that you need high-rated segments-matches, angles, and promos? Push your talent better. ![]() There are a handful of stats for each wrestler and it’s pretty easy to figure out who you should book against who for the best match.ĭo you need good promos? Put the guy on with the best mic skills. The game comes with a tutorial but honestly, starting a new game and playing around with it for the first month of booking, you’ll get the hang of things. It has difficulty but once you get the grasp of it, it’s one of the easiest games in the franchise. The other thing is that it’s an easy game all around. It didn’t become a franchise until Total Extreme Warfare 2004 dropped. The reason we’re on a game that came out in the early 2000s is that EWR is still the most loved of the franchise. #Extreme warfare revenge updated roster seriesNow, the current series in the franchise- Total Extreme Wrestling -just released the 2020 edition earlier in the year. It was originally meant to be a wrestling card game but ended up becoming the root for the gold standard in booking sims.įollowing the Extreme Warfare and Extreme Warfare Deluxe games, Ryland continued the text-based simulation series with Extreme Warfare Revenge. ![]() Booking sims are basically fantasy booking with a challenge-usually for the game’s AI.īritish indie programmer Adam Ryland had been busy with the Extreme series since 1995. Ī mobile series such as Checkmate’s Mania Wrestling series also hinges on booking. #Extreme warfare revenge updated roster proOr the Fire Promoter mode in Fire Pro Wrestling World. There are wrestling simulators that included this element. This is simply the skinny of it.Įssentially, it’s a wrestling-oriented business management game. In this role, you’re tasked with creating interesting cards and making money for your organization. Extreme Warfare Revenge: The Big Leap For Booking SimsĪ booking sim is a wrestling or MMA game where you’re in the role of either the owner or promoter. Let’s go back to the early 2000s with Extreme Warfare Revenge. One subgenre of wrestling games that get a little love-but deserves more-is the booking sim. On GameStingr, you’ll notice a lot of stuff about wrestling games. ![]() ![]() And in a rarity for Disney Plus, the documentary contains explicit language, mature themes and smoking. Jackson did not interview the surviving Beatles, McCartney and Starr, for the docuseries, wanting to remain in the moment, in the room, on the rooftop in 1969. ![]() ![]() The docu-series shows, for the first time, The Beatles' last live performance as a group - the rooftop concert on London’s Savile Row. With their backs against the wall, the Beatles rely on their bonds, good humor and creative genius to hit the deadline. The lp release in UK was Today, 8th May 1970 Let it Be The film, which was shot in January 1969, was originally intended to be a TV special called Get Back featuring the group rehearsing for their first live show in over two years. The Beatles film will focus on the making of the band’s penultimate studio album ‘Let It Be. ![]() Get Back takes audiences back to the somewhat-frenzied time when the band was trying to write 14 new songs for their first live concert in two years. The Beatles film Let It Be had its premiere in New York 48 years ago. Disney + have announced plans to stream Peter Jackson’s new The Beatles: Get Back documentary. The Beatles (from left, Paul McCartney, George Harrison, Ringo Starr and John Lennon) work on new music in Peter Jackson’s new docuseries The Beatles: Get Back streaming Nov. #Let it be the beatles documentary stream how toView Deal How to watch The Beatles: Get Back in the UK, Canada and other international regionsĭisney Plus is available in Australia, Austria, Belgium, Canada, Denmark, Finland, France, Germany, Iceland, India, Indonesia, Ireland, Italy, Japan, Luxembourg, Mauritius, Monaco, Netherlands, New Zealand, Norway, Portugal, Spain, Sweden, Switzerland and the United Kingdom, so it's not going to be tough to get access. ![]() ![]() ![]() Her results show equal attributes of multiple factions, which means that she is Divergent. Beatrice takes her test with a Dauntless woman, Tori Wu ( Maggie Q), as her proctor. Her father, Andrew Prior ( Tony Goldwyn), serves on the ruling council along with the head of Abnegation, Marcus Eaton ( Ray Stevenson). When children reach the age of 16, they undergo a serum-induced psychological aptitude test which indicates their best-suited faction, but they are allowed to choose any faction as their permanent group at the subsequent Choosing Ceremony.īeatrice Prior ( Shailene Woodley) was born into Abnegation, which runs the government. ![]() The remaining population are the Factionless, who have no status or privilege in this society. In the futuristic city of dystopian Chicago, society is divided into five factions: Abnegation (the selfless), Amity (the peaceful), Candor (the honest), Dauntless (the brave), and Erudite (the intellectual).
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